Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...
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Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
Some genome editing systems are highly conspicuous. They introduce double-strand breaks to DNA that attract the attention of cellular mechanisms such as nonhomologous end joining and homology-directed ...
In a recent study posted to the bioRxiv* pre-print server, researchers proposed a structural mechanism to explain immune evasion effects of the two-point mutations, S371L and S371F, in the ...
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