Bacteria utilise a sophisticated chemical communication system, known as quorum sensing, to assess their population density and coordinate group behaviours, including the formation of biofilms. This ...
Bacteria grow on surfaces in complex immobile communities known as biofilms, which are composed of cells embedded in an extracellular matrix. Within biofilms, bacteria often interact with members of ...
Heart valve infections are difficult to cure because bacteria hide in biofilms that resist antibiotics. This study reveals that E. faecalis can grow more aggressively when it loses a key communication ...
Microbial biofilms represent one of the most formidable challenges in modern medicine, industry, and environmental systems. These structured, ...
The focus of my research is in mathematical and computational biology with particular applications in ecology, infectious diseases, and agriculture through modeling, analysis, and simulations.
Pseudomonas aeruginosa uses the quorum sensing (QS) system to regulate virulence factors expression and biofilm development. Researchers from Jinan University reported on novel inhibitors of P.
PqsE is a putative metallohydrolase protein, which positively regulates pyocyanin biosynthesis as well as biofilm formation. The biosynthesis of pyoverdine can be positively impacted by the biofilm ...
Pseudomonas aeruginosa is notorious for its role in food spoilage and infections, posing a significant threat to both food safety and human health. Traditionally, antimicrobial agents have been the go ...
Pseudomonas aeruginosa biofilm development occurs in five stages. 1. Reversible attachment: Cells transiently affix to substratum, and surface induced gene expression results in a protein profile ...
It has been reported that the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) for biofilm bacteria are 10 to 1000 times higher than the corresponding values for ...
Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for ...