Analysis of 5&-reductase(5&R) is commonly done by measurement of distinct testosterone(T) metabolites, following tissue incubation. Interlaboratory comparison is difficult, as different individual ...

Cells send signals through enzyme cascades, where one enzyme passes the signal to the next. In such cascades, it is crucial that the enzyme recognizes the right substrates to ensure that, for example, ...

Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...

The 1 H NMR NMR spectrum of the hydrolysis reaction shown in figure 1 illustrates the depletion of the substrate N-acetyl-DL-methionine (4.25ppm), and the simultaneous appearance of the product ...

Without enzymes, an organism would not be able to survive. It is these biocatalysts that facilitate a whole range of chemical reactions, producing the building blocks of the cells. Enzymes are also ...

In order to sustain themselves, living organisms rely on proteins called enzymes to catalyze the necessary organic reactions. This reaction process begins when the substrate (S) reversibly binds to ...

Enzymes are biological catalysts that facilitate biochemical transformations. An international team of bioinformatics researchers has developed a new process for predicting Michaelis constants, which ...